As one of the important treatments of health care and anti-aging in traditional Chinese medicine (TCM), moxibustion has been proved to have the effects of scavenging free radicals, anti-oxidation, reducing inflammatory reaction, regulating immunity and so on. Recent studies have shown that intestinal microbiota affect the process of aging. The …
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Harvard scientists discovered the neuroanatomical basis for acupuncture points that trigger a specific anti-inflammatory signaling pathway, advancing the understanding of acupuncture’s therapeutic potential. The team, led by Harvard Medical School neurobiologists, found the specific type of neuron — “PROKR2-Cre marked sensory neurons” — that must be present for acupuncture to …
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Objective: To observe the effect of electroacupuncture at Neiguan (PC 6) on cardiac function and cardiomyocyte apoptosis in rats with acute myocardial ischemia (AMI), and to explore the correlation between myocardial protective effect of EA and inflammatory factors i.e. interleukin-1β (IL-1β) and interleukin-17 (IL-17) of Neiguan (PC 6) area. Methods: A total …
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Electroacupuncture is considered to have potential antidiabetic effects; however, the role of the pancreatic intrinsic nervous system (PINS) in electroacupuncture-induced amelioration of type 2 diabetes (T2DM) remains unclear. Therefore, we investigated whether electroacupuncture at ST25 exerts any beneficial effects on insulin resistance (IR), inflammation severity, and pancreatic β cell function …
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Objective: To investigate whether blood-brain barrier served a key role in the edema-relief effect of bloodletting puncture at hand twelve Jing-well points in traumatic brain injury and the potential molecular signalling pathways. Methods: Adult male Sprague-Dawley rats were assigned to the sham-operated (sham), traumatic brain injury, and bloodletting puncture (bloodletting) groups (n=24 …
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Objective: To explore the mechanism of acupuncture in improving cognitive ability by regulating hippocampal phosphatidylinositol-3 kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway in vascular dementia rats. Methods: A total of 80 male SD rats were randomized into sham operation, model, non-acupoint and acupoint groups (n=18 per group). The VD …
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Objective: To observe the effect of long-term inhalation of moxa-smoke on olfactory epithelial cells in rats, in order to explore the safety of moxa-smoke inhalation. Methods: A total of 32 SD rats (half male and half female) were randomly divided into 4 groups: normal, low concentration (LCMSI), medium concentration (MCMSI) and high …
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Acupuncture and moxibustion have definite clinical effects on treating ulcerative colitis, but their mechanism is still unclear. To investigate the molecular mechanisms, we applied herb-partitioned moxibustion or electroacupuncture at the Tianshu (ST25) points on UC rats and used RNA sequencing to identify molecular consequences. Male Sprague Dawley (SD) rats were …
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Methods: A total of 51 C57BL/6N mice were randomized into a 7-day control group (n=8), a 7-day model group (n=7), a 7-day moxibustion group (n=7), a 14-day control group (n=6), a 14-day model group (n=14) and a 14-day moxibustion group (n=9). In the model groups and the moxibustion groups, 2% dextran …
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Forty-eight SD rats were randomly divided into control, model, EA and inhibitor groups (n=12 in each group). The CFS model was established by multi-factor compound stress stimulation method. Rats of the EA group received EA (50 Hz, 1 mA) at “Baihui” (GV20), Emotional Area I and bilateral Sensory Area for …
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