Background: Electroacupuncture (EA) is used to treat inflammatory bowel disease (IBD). Nevertheless, the precise mechanisms by which this approach safeguards against obesity-induced intestinal barrier damage has not been fully understood. Objective: This study aimed to assess whether electroacupuncture could ameliorate intestinal barrier damage that had been reversed in a mouse model of …
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Background: Metabolic defects play a crucial role in Alzheimer’s disease (AD) development. Brown adipose tissue (BAT) has been identified as a novel potential therapeutic target for Alzheimer’s disease due to its unique role in energy metabolism. Electroacupuncture (EA) shows promise in improving cognitive ability and brain glucose metabolism in Alzheimer’s disease, …
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Introduction: Adjusting internal organs and dredging channel electroacupuncture has a definite effect on type 2 diabetes, but the specific mechanism still needs to be further clarified. This study aims to investigate the effects of electroacupuncture on the gut microbiota and bile acids in db/db mice after the intervention of “adjusting internal …
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Objective: To observe the efficacy of moxibustion in the treatment of chronic fatigue syndrome (CFS) and explore the effects on gut microbiota and metabolic profiles. Methods: Forty-eight male Sprague-Dawley rats were randomly assigned to control group (Con), chronic fatigue syndrome model group (Mod, established by multiple chronic stress for 35 d), MoxA …
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Electroacupuncture (EA) is widely applied in clinical therapy for spinal cord injury (SCI). However, the associated molecular mechanism has yet to be elucidated. The current study aimed to investigate the underlying mechanism of electroacupuncture in neurological repair after spinal cord injury. Firstly, we investigated the role of electroacupuncture in the …
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Autophagy is a well conserved metabolic system that maintains homeostasis by relying on lysosomal breakdown. Both the endometrium of patients with intrauterine adhesion (IUA) and an animal model exhibit impaired autophagy. Autophagy is negatively correlated with inflammation. Activation of autophagy can inhibit the inflammatory response, while defects in autophagy will …
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Chronic itch severely reduces the quality of life of patients. Electroacupuncture is widely used to treat chronic itch. However, the underlying mechanism of this therapeutic action of electroacupuncture is largely unknown. Cannabinoid CB1 receptors in the ventrolateral periaqueductal gray (vlPAG) mediate the analgesic effect of EA. Using a dry skin-induced …
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Premature ovarian failure is the leading cause of female infertility, and there is no optimal treatment or medication available currently. For premature ovarian failure, electroacupuncture has been considered a promising therapeutic approach, but the mechanism for this is not clear. In this study, we explored the effects of electroacupuncture (CV4, …
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Introduction: Oxidative stress is involved in the occurrence and development of multiple diseases. Acupuncture shows an excellent clinical efficacy in practical application but its mechanism remains unclear. This systematic review and meta-analysis was aimed at assessing the effect of acupuncture on oxidative stress in animal models. Methods: PubMed, Embase, and Web of …
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Background: With the improvement of people’s living standards, how to maintain health and delay aging to improve the quality of life and achieve longevity has become a hot topic of concern. objective. To investigate the effect of acupuncture combined with exercise on the expression of immune factors in aging rats and its …
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