Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism and follicular arrest. Electroacupuncture has been shown to be effective at improving hyperandrogenism and follicular arrest in PCOS; however, its mechanism of action remains to be deciphered. Objective: In this study, we investigated whether electroacupuncture improved follicular development in …
Read More »
Cell pyroptosis is one of the main forms of neuronal injury after cerebral ischemia-reperfusion. It is accompanied by an inflammatory reaction and regulated by the caspase gene family. Electroacupuncture can reduce neuronal injury caused by cerebral ischemia-reperfusion, and we speculated that electroacupuncture can prevent neuronal pyroptosis after cerebral ischemia-reperfusion by …
Read More »
Background: Osteoarthritis is a difficult disease but the clinic lacks effective therapy. As a classic formula of traditional Chinese medicine (TCM), Fu Zi Tang has been clinically applied for treating osteoarthirtis-related syndromes, but its anti-oesteoarthirtis efficacy and mechanism remain unclear. Purpose: To experimentally and clinically determine the anti-osteoarthritis efficacy of Fu Zi …
Read More »
Objectives: To study whether moxibustion can improve the learning and memory ability of APP/PS1 mice by reducing the pathological products Aβ and Tau protein via decreasing N6-methyladenosine (m6A). Methods: APP/PS1 mice were randomly divided into model group (APP/PS1) and moxibustion group (APP/PS1+Mox). C57BL/6J mice were used as a control group (Control). Learning and …
Read More »
Background: The clinical treatment of ulcerative colitis is limited. A traditional Chinese medicinal formula, Huang Qin Tang, is chronicled in Shang Han Lun and is widely used to ameliorate gastrointestinal disorders, such as ulcerative colitis; however, its mechanism is yet to be clarified. Purpose: The present study aimed to investigate the effect …
Read More »
Objective: Moxibustion, a common therapy in traditional Chinese medicine, has potential benefits for treating decreased ovarian reserve. The present study investigates the protective effect of moxibustion in a rat model of decreased ovarian reserve and explores the possible mechanisms. Methods: Sixty-four female Sprague-Dawley rats were randomly divided into four groups: control, decreased …
Read More »
Background: The pathogenesis of depression remains largely unknown. Accumulating evidence demonstrates the existence of a complex relationship between gut microbiome composition and brain functions. Jia Wei Xiao Yao San is considered a potential antidepressant. However, the pharmacological mechanisms of Jia Wei Xiao Yao San have not yet been clarified. Purpose: This study …
Read More »
Depression is characterized by indifferent and slow thinking, leading to highly unfavorable social and economic burden. Hong Hua is a traditional Chinese medicine and has many pharmacological properties, such as anti-oxidative and anti-inflammatory activities. However, the underlying mechanism unraveling the effect of Hong Hua on depression is still unclear. Here, …
Read More »
Background: Evidence has shown that the traditional Chinese herbal medicine Wu Mei Wan has a protective effect on ulcerative colitis. Here, we studied the anti-inflammatory effects and potential mechanisms of Wu Mei Wan on chronic colitis in mice. Methods: A dextran sulfate sodium (DSS)-induced chronic colitis model and CD45RBhighCD4+ T cell transfer …
Read More »
Polycystic ovarian syndrome (PCOS) is a common, complex, and heterogeneous endocrine and metabolic disorder. There is no standardized treatment, and it therefore requires individualized therapies according to the symptoms and pathogenesis of each patient. The present study aimed to determine the effect of electroacupuncture at the acupoints Zusanli (ST36), Sanyinjiao …
Read More »
Acupuncture Times Your guide to acupuncture, Chinese herbal medicine and TCM — explore acupoints, herbs and formulas, plus the latest acupuncture research news.