Tag Archives: Animal Study

Paraventricular hypothalamus is demonstrated to regulate stress, feeding behaviors, and other related homeostatic processes. However, no direct evidence has been investigated for the role of pentricular hypothalamus in swallowing function. Acupuncture therapy at Lianquan (CV 23) acupoint has been reported to improve the swallowing function in clinical trials, but its …

Objective: To observe and compare the effects of different acupuncture and moxibustionmethods at “San-yinjiao” (SP6) on uterine contraction and microcirculation in cold congealing dysmenorrhea rats, so as to explore its mechanism underlying treatment of dysmenorrhea. Methods: A total of 140 female SD rats were randomly divided into normal control, mo-del, perpendicular needling, …

Objective: To observe the effects of moxibustion on “Shenshu” and “Zusanli” on macrophage polarization and IL-4/STAT6 signaling pathway in rats with rheumatoid arthritis. To further explore the possible anti-inflammatory mechanism of moxibustion in the treatment of rheumatoid arthritis. Methods: The rats’ right hind paws were injected with freund’s complete adjuvant (FCA) to …

Objective: To observe the effect of electroacupuncture on the expression of myocardial protein kinase B (Akt) and mammalian target of rapamycin (mTOR) in acute myocardial ischemia rats. Methods: Thirty male SD rats were randomly divided into control, model and electroacupuncture groups (n=10 in each group). The acute myocardial ischemia model was established …

Objective: To observe the effect of ZhuLian’s type Ⅱ inhibition needling technique on sex hormones, insulin resistance and ovarian morphology in rats with polycystic ovary syndrome (PCOS), so as to explore its mechanism on regulating endocrine and metabolic dysfunction of PCOS. Methods: Twenty-four female SD rats were randomly divided into control, model …

Background: Huo Xiang Zheng Qi oral liquid , a pharmaceutical product made from traditional Chinese medicine formulas, has been commonly used in household medication for gastrointestinal disorders, but the mode of action remains largely unclear. Purpose: This study aims to investigate whether pretreatment with Huo Xiang Zheng Qi prevents lipopolysaccharide-induced adverse effects …

Ethnopharmacological relevance: In the practice of traditional Chinese medicine, endometriosis is believed to be caused by blood stasis and is characterised by dysmenorrhea, which is difficult to control. Shi Xiao San has a long history of use in the treatment of gynaecological diseases. The prescriptions composed of Shi Xiao San include …

Controlled ovarian hyperstimulation impairs the endometrium receptivity during the implantation window, resulting in a lower clinical pregnancy rate and a higher abortion rate. Our study explored the effect of electroacupuncture on the endometrial receptivity of COH rats. Female rats were randomly divided into normal treatment (Normal), model treatment (Model), low-frequency …

Background and aims: Intestinal fibrosis is one of the severe and common complications of Crohn’s disease, but the etiology and pathogenesis remain uncertain. The study intended to examine whether the effect of herb-partitioned moxibustion on rats with Crohn’s disease-associated intestinal fibrosis is associated with the RhoA/ROCK1/MLC pathway. Methods: All experimental rats were …

As one of the important treatments of health care and anti-aging in traditional Chinese medicine (TCM), moxibustion has been proved to have the effects of scavenging free radicals, anti-oxidation, reducing inflammatory reaction, regulating immunity and so on. Recent studies have shown that intestinal microbiota affect the process of aging. The …