Tag Archives: Neuroprotection

Ethnopharmacological relevance: Alcohol misuse persists as a prevalent societal concern and precipitates diverse deleterious consequences, entailing significant associated health hazards including acute alcohol intoxication (AAI). Binge drinking, a commonplace pattern of alcohol consumption, may incite neurodegeneration and neuronal dysfunction. Clinicians tasked with managing acute alcohol intoxication confront a dearth of pharmaceutical …

Cell pyroptosis is one of the main forms of neuronal injury after cerebral ischemia-reperfusion. It is accompanied by an inflammatory reaction and regulated by the caspase gene family. Electroacupuncture can reduce neuronal injury caused by cerebral ischemia-reperfusion, and we speculated that electroacupuncture can prevent neuronal pyroptosis after cerebral ischemia-reperfusion by …

The incidence and disability rate of spinal cord injury worldwide are high, imposing a heavy burden on patients. Considerable research efforts have been directed toward identifying new strategies to effectively treat SCI. Governor Vessel electro-acupuncture, used in traditional Chinese medicine, combines acupuncture with modern electrical stimulation. It has been shown …

Alzheimer’s disease, as one of most common dementia, mainly affects older people from the worldwide. In this study, we intended to explore the possible mechanism of improving cognitive function and protecting the neuron effect by electroacupuncture. Method: We applied senescence-accelerated mouse prone 8 (SAMP8) mice as Alzheimer’s disease animal model, used …

Methods: The active components and targets of Huang Qi Si Jun Zi Tang were searched in the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). The genes corresponding to the targets were retrieved using UniProt and GeneCard database. The herb-compound-target network and protein-protein interaction (PPI) network were constructed by …

The present study aims to assess the neuroprotective effects of Qing yang shen, a Chinese herbal medicine, in Alzheimer’s disease cellular and animal models and to determine its underlying mechanisms involving ALP regulation. Methods: Qing yang shen extract was prepared and its chemical components were characterized by LC/MS. Then the pharmacokinetics …