Ethnopharmacological relevance: Clinical research and basic scientific experiments have shown that modified Xiao Yao San (MXYS) has antidepressant effects, whose system mechanism however has not been thoroughly characterised. Aim of the study: This research was aimed at evaluating the treatment effects of Xiao Yao San on chronic unpredictable mild stress (CUMS)-induced depressive …
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Xiao Yao Wan has been widely applied in China to treat stress-related illnesses, such as migraine, depression, Parkinson’s disease, insomnia, hypertension. In this study aims to explore the effect of Xiao Yao Wan on chronic unpredictable mild stress-induced depression and its underlying mechanisms. Chronic unpredictable mild stress-induced depression rat models were established, …
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The Nod-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome-driven inflammatory response plays a key role in the pathophysiology of depression. Mounting evidence suggests that acupuncture is an effective treatment for depression. In this study, we investigated the effects of acupuncture treatment at the acupoints Baihui (GV20) and Yintang (GV29) on …
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