Research

Benefiting from the development of network pharmacology, Traditional Chinese Medicine (TCM) shows great potential in modern drug discovery. Recently, more and more TCM-related databases have been established for both academic and industry research, but they are still insufficient in data standardization, integrity, and precision. To better accelerate the TCM research …

Ethnopharmacological relevance: Obesity in patients with schizophrenia is related to antipsychotic drug use, hypertension, diabetes, and dyslipidemia, which are critical risk factors for cardiovascular disease. Cassia seed is a traditional Chinese medicine that can be used to treat various eye disorders. Anthraquinone-containing Cassia seed were used to lower serum levels of …

Coronavirus disease 2019 (COVID-19) is an acute respiratory infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and it has become a public health concern worldwide. In addition to respiratory symptoms, some COVID‑19 patients also show various gastrointestinal symptoms and even consider gastrointestinal symptoms to be the first …

Traditional Chinese Medicine (TCM) plays a role in preventing and treating COVID-19 in China. Based on the manifestations and symptoms of COVID-19, our study used the data mining method to summarize related therapeutic experience left by predecessors who used TCM to treat epidemics in their eras. Initially, we collected abundant …

Background: Chemotherapy-induced peripheral neuropathy is a common adverse reaction of chemotherapy. Many studies have confirmed that traditional Chinese medicine (TCM) has unique advantages for treating CIPN. However, there is no standard TCM prescription in clinical practice or objective outcome index, and similar efficacy varies. In this study, a systematic review of …

Ethnopharmacological relevance: The incidence and mortality of bronchial asthma are increasing, and RSV is widely regarded as the common cause of clinical exacerbation of asthma. Ma Xing Gan Shi Tang, a classic traditional Chinese medicine prescription, is well-known for treating respiratory diseases, while the mechanism of effecting on RSV-exacerbated asthma remains …

Background: Chinese herbs for supplementing qi and activating blood circulation combined with N-acetylcysteine (NAC) is widely used for idiopathic pulmonary fibrosis in China, but there is a lack of literature to evaluate its efficacy and clinical value. Purpose: This study compared Chinese herb + NAC with other treatments by network meta-analysis to …

Background: Gui Zhi Gan Cao Long Gu Mu Li Tang can make a good effect on the insomnia under the catalogue of traditional Chinese medicine. Method: To search the databases:Pubmed, Web of Science, EMBASE, the Cochrane Library, the China National Knowledge Infrastructure (CNKI), the China Biology Medicine disc (CBMdisc), the China Science …

The gut microbiota and metabolites are important factors in mediating the development of type-2 diabetes mellitus. An imbalance in the gut microbiota and metabolites can disrupt the function of the intestinal barrier, cause changes in the permeability of the intestinal mucosa and promote the immune inflammatory response, thereby aggravating the …

Ethnopharmacological relevance: Xiao Jin San was first recorded during the Qing Dynasty and have a history of nearly 300 years. It is the first choice among Chinese patent medicines for the clinical treatment of diseases of the mammary glands in contemporary traditional Chinese medicine. It was also widely used in the …