Background: Osteoarthritis is a difficult disease but the clinic lacks effective therapy. As a classic formula of traditional Chinese medicine (TCM), Fu Zi Tang has been clinically applied for treating osteoarthirtis-related syndromes, but its anti-oesteoarthirtis efficacy and mechanism remain unclear. Purpose: To experimentally and clinically determine the anti-osteoarthritis efficacy of Fu Zi …
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Bupleurum chinense DC. (Chaihu) is a traditional Chinese medicine (TCM) used in the treatment of anxiety. But the anxiolytic mechanisms of bupleurum are still unclear. Therefore, this unknown is predicted by network pharmacology study with molecular docking in the present study. The components of bupleurum were obtained from the databases. …
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Background: Coronavirus disease 2019 (COVID-19) keeps spreading globally. Chinese medicine (CM) exerts a critical role for the prevention or therapy of COVID-19 in an integrative and holistic way. However, mining and development of early, efficient, multisite binding CMs that inhibit the cytokine storm are imminent. Methods: The formulae were extracted retrospectively from …
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Background: Traditional Chinese medicine (TCM) is a type of alternative medicine that has been widely utilized in the prevention and treatment of mental diseases such as schizophrenia, ADHD, Alzheimer’s disease, and Tourette’s syndrome in many countries. However, the evidence regarding TCM’s effectiveness and safety in treating Tourette’s syndrome are conflicting. Therefore, …
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Background: Complementary and alternative therapy is widely used to treat chronic obstructive pulmonary disease (COPD). A Chinese herbal medicine, Jian Pi Yi Fei Wan, have been shown to improve COPD patients’ quality of life, however long-term effectiveness has not been examined. Purpose: To investigate whether long-term treatment with Jian Pi Yi Fei …
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Background: The clinical treatment of ulcerative colitis is limited. A traditional Chinese medicinal formula, Huang Qin Tang, is chronicled in Shang Han Lun and is widely used to ameliorate gastrointestinal disorders, such as ulcerative colitis; however, its mechanism is yet to be clarified. Purpose: The present study aimed to investigate the effect …
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Sjögren’s syndrome is an autoimmune disease, and its conventional treatment has exhibited limited therapeutic efficacy. Qing Zao Fang, a traditional Chinese medicine formula, is used in the treatment of Sjögren’s syndrome, but its chemical composition is complex, and its pharmacological mechanism is not clear. Therefore, this study aims to explore …
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Background: Da Huang Zhe Chong San improves the inhibitory immune status of mice with hepatocellular carcinoma by regulating Treg/Th1 balance. Hypothesis/purpose: To study the multi-material basis and multi-mechanisms of Da Huang Zhe Chong San against hepatocellular carcinoma by regulating Treg/Th1 balance in vitro and in vivo. Methods: UPLC-MS/MS was used to detect the …
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Purpose: This study aims to evaluate the effectiveness and safety of oral Chinese herbal medicine in the treatment of knee osteoarthritis. Study design: Systematic review and meta-analysis of randomized controlled trials (RCTs). Materials and methods: A computer was used to retrieve all RCTs of Chinese herbal medicine in the treatment of knee osteoarthritis …
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Background: Since the beginning of the Coronavirus disease 2019 (COVID-19) pandemic, various complementary and alternative medicines have been used in clinical practice. In this overview, we summarized the evidence for complementary and alternative medicines interventions in the treatment of COVID-19 patients. Methods: For this overview, PubMed, Embase and Cochrane Library were searched …
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