Long noncoding RNA (lncRNAs) are involved in the pathogenesis of ulcerative colitis. Moxibustion, a traditional Chinese medicine, can improve symptoms in patients with ulcerative colitis and reduce intestinal inflammation in rats with ulcerative colitis. However, it remains unclear whether the ameliorative effect of moxibustion on intestinal mucosal inflammation in ulcerative …
Read More »Electroacupuncture improves ulcerative colitis
Objective: To evaluate the efficacy and safety of electroacupuncture on ulcerative colitis and explore the influence of electroacupuncture parameters and acupoint compatibility to optimise the clinical treatment plan. Methods: After searching eight databases, data were extracted and analyzed to determine the quality and bias of the study’s methodological design, and randomized controlled …
Read More »Gan Cao aids in the treatment of ulcerative colitis
Ethnopharmacological relevance: Licorice, as a traditional Chinese herbal medicine, possessing the efficacies of invigorating spleen and replenishing qi, heat-clearing and detoxicating, phlegm-resolving and cough suppressant, relieving spasm and pain, and hamonizing actions of various medicines. Aim of the study: The goal of this systematic review, which includes meta-analysis and network pharmacology in …
Read More »The Chinese herbal formula Huang Qin Tang relieves ulcerative colitis
Background: The clinical treatment of ulcerative colitis is limited. A traditional Chinese medicinal formula, Huang Qin Tang, is chronicled in Shang Han Lun and is widely used to ameliorate gastrointestinal disorders, such as ulcerative colitis; however, its mechanism is yet to be clarified. Purpose: The present study aimed to investigate the effect …
Read More »The Chinese herbal formula Wu Mei Wan is effective for ulcerative colitis
Background: Evidence has shown that the traditional Chinese herbal medicine Wu Mei Wan has a protective effect on ulcerative colitis. Here, we studied the anti-inflammatory effects and potential mechanisms of Wu Mei Wan on chronic colitis in mice. Methods: A dextran sulfate sodium (DSS)-induced chronic colitis model and CD45RBhighCD4+ T cell transfer …
Read More »How the Chinese herbal formula Huang Qin Tang is effective for ulcerative colitis
Huang Qin Tang is a Traditional Chinese Medicine formula for ulcerative colitis. However, the pharmacology and molecular mechanism of Huang Qin Tang on ulcerative colitis is still unclear. Combined microarray analysis, network pharmacology, and molecular docking for revealing the therapeutic targets and molecular mechanism of Huang Qin Tang against ulcerative …
Read More »Acupuncture and moxibustion are effective in the treatment of ulcerative colitis
Acupuncture and moxibustion have definite clinical effects on treating ulcerative colitis, but their mechanism is still unclear. To investigate the molecular mechanisms, we applied herb-partitioned moxibustion or electroacupuncture at the Tianshu (ST25) points on UC rats and used RNA sequencing to identify molecular consequences. Male Sprague Dawley (SD) rats were …
Read More »Moxibustion helps ulcerative colitis
Methods: A total of 51 C57BL/6N mice were randomized into a 7-day control group (n=8), a 7-day model group (n=7), a 7-day moxibustion group (n=7), a 14-day control group (n=6), a 14-day model group (n=14) and a 14-day moxibustion group (n=9). In the model groups and the moxibustion groups, 2% dextran …
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