Background: Dynamic orchestration of metabolic pathways during continuous fasting remains unclear. Objective: We investigated the physiological effects of Bigu-style fasting and underlying metabolic reprogramming in healthy adults. Methods: We conducted a 5-d Bigu trial in 43 healthy subjects [age 23.2 ± 2.4 y; BMI (in kg/m2) 22.52 ± 1.79]. Physiological indicators and body …
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