Tag Archives: chinese herbs

Objective: To explore the molecular mechanism mediating the inhibitory effect of Chuanxiong Rhizoma against brain metastasis of lung cancer using network pharmacology methods and molecular docking. Methods: The chemical components of Chuanxiong Rhizoma and their targets were obtained through the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database. The relevant targets for brain metastasis of lung cancer …

Botanicals used in Traditional Chinese Medicine (TCM) are a rich source for drug discovery and provide models for multi-component drug development. To facilitate the studies of the actions of TCM drugs and expand their applications, a comprehensive database is urgently required. Methods: One online resource connects all the relevant data from …

Methods: The active components and targets of Huang Qi Si Jun Zi Tang were searched in the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). The genes corresponding to the targets were retrieved using UniProt and GeneCard database. The herb-compound-target network and protein-protein interaction (PPI) network were constructed by …

Objective: To assess the clinical efficacy of Chinese herbal medicine for removing blood stasis combined with acupuncture in the treatment of sequelae of cerebral infarction. Methods: Ninety patients with cerebral infarction admitted to our hospital from April 2018 to April 2020 were enrolled and equally allocated to an experimental group and a …

This review aimed to summarize and analyze the pattern identification (PI), herbal formulae, and composition of herbs provided by recent guidelines for the treatment of pediatric COVID-19. Seven data sources were reviewed until March 25, 2020. We analyzed the herbal formulae included in the guidelines and performed a network analysis …

Objective: To compare the efficacy of Chinese herbal medicine or Chinese herbal medicine plus indomethacin with that of indomethacin alone in treating polyhydramnios. Methods: Literatures published up to April 2012 were retrieved from PubMed, Embase and Cochrane library, Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific and Technological Periodical Database (VIP), Wangfang, and …

The quality control of Chinese herbal medicines (CHM) is a key concern on the modernization and globalization. However, it is still a difficult task due to its multi-component, multi-target, multi-pathways. This study aims to provide a novel and comprehensive strategy for quality control in complex Chinese medicines (CHM) formulas by …

A Chinese herbal formula used to treat coronavirus patients in China is undergoing clinical trials in the US for possible approval for people with mild-to-moderate symptoms of the viral disease. Qingfei Paidu, most commonly called QFPD, is a 21-herb formula whose name literally means “lung cleansing and detoxification.”  The US …

Xiao Chai Hu Tang (Soshiho-tang) is a traditional herbal medicine that has anti-inflammatory effects and improves immune function. This clinical trial evaluated the efficacy and safety of Xiao Chai Hu Tang in atopic dermatitis patients with gastrointestinal disorders in comparison with placebo. Materials and methods: This study was a single-center, randomized, …

The present study aims to assess the neuroprotective effects of Qing yang shen, a Chinese herbal medicine, in Alzheimer’s disease cellular and animal models and to determine its underlying mechanisms involving ALP regulation. Methods: Qing yang shen extract was prepared and its chemical components were characterized by LC/MS. Then the pharmacokinetics …