Background: This study aims to analyze the mechanism of Gua Lou Xie Bai Gui Zhi Tang in treating coronary heart disease utilizing network pharmacology. Methods: The Gua Lou Xie Bai Gui Zhi Tang effective components were searched on the pharmacological database platform of the Traditional Chinese Medicine Systems Pharmacol, and its potential …
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Diarrhea predominant irritable bowel syndrome (IBS) is a highly relapsing gastrointestinal disorder decreasing the quality of life. Existing studies indicated that the therapeutic effects maintained for a period of time after the treatments were discontinued (post-treatment therapeutic effects or PTTE). In this study, we aim to assess the PTTE of …
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Background: The infertility caused by polycystic ovary syndrome (PCOS) has received considerable attention. Considerable efforts have been made to improve the rates of pregnancy and live birth. Cang Fu Dao Tan Tang is a classic prescription for treating infertility in obese women. The efficacy of Cang Fu Dao Tan Tang in …
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Background: The phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin (PI3K/Akt/mTOR) signalling pathway is crucial for cell survival, differentiation, apoptosis and metabolism. Xi Huang Wan are a traditional Chinese preparation with antitumour properties. They inhibit the growth of breast cancer, glioma, and other tumours by regulating the PI3K/Akt/mTOR signalling pathway. However, the effects …
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Ethnopharmacological relevance: Tao Hong Si Wu Tang is a classic prescription of traditional Chinese medicine that is mainly used for promoting blood circulation and alleviating blood stasis. Tao Hong Si Wu Tang is composed of Prunus persica (L.) Batsch, Carthamus tinctorius L., Ligusticum chuanxiong hort, Angelica sinensis (Oliv.) Diels, Rehmannia glutinosa …
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Ethnopharmacological relevance: Xiao Yao San is a traditional Chinese herbal formula that has long been used to treat liver cirrhosis, liver failure, and hepatocarcinoma. However, little is known about its mechanism of action and targets in treating chronic liver disease. Aim of the study: This study aimed to detect the critical transition …
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Background: Da Huang Zhe Chong Wan improves the inhibitory immune status of mice with hepatocellular carcinoma by regulating Treg/Th1 balance. Hypothesis/purpose: To study the multi-material basis and multi-mechanisms of Da Huang Zhe Chong Wan against hepatocellular carcinoma by regulating Treg/Th1 balance in vitro and in vivo. Methods: UPLC-MS/MS was used to detect the …
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Ethnopharmacological relevance: Traditional Chinese medicine categorizes Mycoplasma pneumoniae pneumonia as “lung heat”, and treatment with heat clear and detoxify. Traditional Chinese medicine believes that the lungs and intestines come from the same source, and the intestine is related to pneumonia. This is the same as the gut-lung axis theory. Qin Bai …
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As a prescription for treating lung inflammation and intestinal diseases, Xuan Bai Cheng Qi Tang in clinical practice can effectively treat COPD with excessive heat in the lung and fu-organs, which is characterized by phlegm-heat accumulation in the lung and constipation. This study aims to find the potential biomarkers of …
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Background: The symptoms of coronavirus disease 2019 (COVID-19) such as hyposmia, rhinorrhea, nasal obstruction, and cough are similar to those of chronic allergic rhinitis. Such symptoms can easily lead allergic rhinitis patients to unnecessary anxiety, misdiagnosis, and invasive diagnostic tests in the COVID-19 pandemic. Interleukin-6 (IL-6) is an important mediator for …
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