Background: Acupuncture treatment of chronic insomnia was effective. Anxiety and depression symptoms of the chronic insomnia patients were improved to varying degrees after acupuncture treatment. Corticosterone and 5-hydroxytryptamine are involved in the occurrence and development of comorbidity of insomnia, anxiety, and depression. Whether acupuncture can treat insomnia and accompany anxiety and …

Background: Irritable Bowel Syndrome, as a functional gastrointestinal disorder, is characterized by abdominal pain and distension. Recent studies have shown that acupuncture treatment improves symptoms of diarrhea-predominant irritable bowel syndrome by altering networks in certain brain regions. However, few studies have used resting-state functional magnetic resonance imaging (fMRI) to compare altered …

Objective: To evaluate the curative effect of integrated Traditional Chinese and Western Medicine on gout, and to investigate the therapy timing and exact treatment options of integrated medicine. Methods: Totally 860 patients were enrolled, including 460 patients with intermittent gout, 200 patients with active Traditional Chinese Medicine (TCM) syndrome (TCM syndrome score …

Objective: To investigate whether blood-brain barrier served a key role in the edema-relief effect of bloodletting puncture at hand twelve Jing-well points in traumatic brain injury and the potential molecular signalling pathways. Methods: Adult male Sprague-Dawley rats were assigned to the sham-operated (sham), traumatic brain injury, and bloodletting puncture (bloodletting) groups (n=24 …

Objective: To explore the neuromechanism of trans-auricular vagus nerve stimulation for treatment-resistant depression based on functional brain network. Methods: Twenty-eight patients with treatment-resistant depression were recruited from the psychiatric clinic or by the advertisement. The patients were treated by taVNS (5 Hz/20 Hz, 4-8 mA) at the auricular concha for 30 min, …

Objectives: Sexual dysfunction can adversely affect the quality of life and interpersonal relationships. nowadays, a lot of attention is paid to traditional Chinese medicine with better curative effects and less adverse events. Recent studies have implied the promising effect of acupuncture on sexual function. This systematic review evaluate the effectiveness and …

Objective: To explore the mechanism of acupuncture in improving cognitive ability by regulating hippocampal phosphatidylinositol-3 kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway in vascular dementia rats. Methods: A total of 80 male SD rats were randomized into sham operation, model, non-acupoint and acupoint groups (n=18 per group). The VD …

Objective: To observe the effect of long-term inhalation of moxa-smoke on olfactory epithelial cells in rats, in order to explore the safety of moxa-smoke inhalation. Methods: A total of 32 SD rats (half male and half female) were randomly divided into 4 groups: normal, low concentration (LCMSI), medium concentration (MCMSI) and high …

Study objectives: To evaluate the efficacy and safety of acupuncture at HT 7 (Shenmen) and KI 7 (Fuliu) on sleep and comorbid symptoms for chronic insomnia. Methods and design: A randomized, single-blind, parallel and sham-controlled trial consisted of an acupuncture group (n = 41) and a sham acupuncture group (n = 41). …

Primary dysmenorrhoea is the most commonly encountered gynecological problem in reproductive-age women. Acupuncture has been suggested as an effective treatment of primary dysmenorrhea that may modulate descending pain modulation systems. In the present study, we used resting-state functional magnetic resonance imaging to investigate possible changes in descending pain modulation systems …