Background: Mild cognitive impairment (MCI) negatively impacts cognition and dual-task abilities. A physical-cognitive integrated treatment approach could mitigate this risk for dementia. Objective: To compare the effectiveness of cognitively enhanced tai ji quan versus standard tai ji quan or stretching exercise in improving global cognition and reducing dual-task walking costs in older …

Background: Pain is a common, debilitating, and poorly understood complication of sickle cell disease. The need for clinical pain management of sickle cell disease is largely unmet and relies on opioids as the main therapeutic option, which leads to a decreased quality of life (QoL). According to the literature, acupuncture has …

Background: To evaluate the clinical efficacy of acupuncture and moxibustion therapy compared to non-acupuncture therapy in the treatment of simple obesity in adult. Methods: Randomized clinical trials concerning acupuncture and moxibustion therapy as a treatment of simple adult obesity were searched in the following Chinese and English databases: Chinese National Knowledge Infrastructure, …

Using a severe acute pancreatitis (SAP) rat model, the mechanism of electroacupuncture were studied on the intestinal function of pancreatitis. The SAP models were established by injecting 30% L-ornithine at hourly intervals, and were divided into two groups (14 in each): SAP model group, which was not treated, and electroacupuncture …

The beneficial effects of Tai Chi on the cardiovascular risk profile and the migraine trigger factors among female migraineurs remain unknown. This study aimed to evaluate the effectiveness of a 12-week Tai Chi training on blood pressure (BP) and migraine-related trigger factors, including stress, fatigue, and sleep quality among Chinese …

Background: Addiction is a chronic/relapsing disorder characterized by compulsive seeking and continuous involvement despite dangerous consequences. It causes long-term changes in the brain. Gambling disorder is a nonsubstance behavioral addiction. An important feature of gambling disorder is maladaptive gambling behavior that is persistent and repetitive, and interferes with patients’ personal lives, …

Background: Obesity can be caused by abnormalities of hypothalamic autophagy, which is closely regulated by the epigenetic modification of TSC1-mTOR. However, whether the weight-reducing effect of electroacupuncture may relate to the modification of TSC1-mTOR methylation and hypothalamic autophagy remain unclear. This study was conducted to reveal the possible mechanism by which …

Objective: To investigate the therapeutic effect of acupuncture stimulation combined with administration of Gu Shen Zhu Yu Tang (decoction for consolidating kidney to eliminate blood stasis) in the treatment of lumbar disc herniation patients. Methods: A total of 147 patients with lumbar disc herniation were randomly divided into Gu Shen Zhu Yu …

Background: Blood-brain barrier (BBB) disruption and gut microbiota dysbiosis play crucial roles in Alzheimer’s disease (AD). Lipopolysaccharide (LPS) stimulation triggered by gut microbial dysbiosis is an important factor in BBB disruption and systemic inflammation, but the mechanism of acupuncture regulation of BBB disruption via the gut microbiota in Alzheimer’s disease is not clear. …

Background: Ping Chan Wan is a traditional Chinese medicine for Parkinson’s disease. Hypothesis/purpose: This was the first study aiming to evaluate the efficacy and safety of Ping Chan Wan for motor symptoms, gait impairments and quality of life in Parkinson’s disease. Study design and methods: In this multicenter, randomized, double-blind, placebo-controlled trial, 292 …