Background and purpose: The occurrence of colorectal cancer is associated with a variety of factors. Accumulating evidence shows that peripheral differentiation of regulatory T cells (Tregs) is critical in controlling tumorigenesis. Our previous studies demonstrated that the Yi Yi Fu Zi Bai Jiang San extract exerted potent anticancer activities by significantly …
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Depression is characterized by indifferent and slow thinking, leading to highly unfavorable social and economic burden. Hong Hua is a traditional Chinese medicine and has many pharmacological properties, such as anti-oxidative and anti-inflammatory activities. However, the underlying mechanism unraveling the effect of Hong Hua on depression is still unclear. Here, …
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Background: Evidence has shown that the traditional Chinese herbal medicine Wu Mei Wan has a protective effect on ulcerative colitis. Here, we studied the anti-inflammatory effects and potential mechanisms of Wu Mei Wan on chronic colitis in mice. Methods: A dextran sulfate sodium (DSS)-induced chronic colitis model and CD45RBhighCD4+ T cell transfer …
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Background: Chemotherapy has become the main means to prolong the life of patients with advanced digestive tract cancer; however, it is associated with serious toxicity and side effects. Compound Ku Shen Injection is a pure Chinese herbal preparation, which can assist chemotherapy, inhibit tumor cell proliferation, and reduce adverse reactions of …
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Background: Polycystic ovary syndrome (PCOS) is a complex polygenic disease and is one of the most common endocrinological and reproductive disorders. The purpose of this study was to evaluate the efficacy of acupuncture combined with herbal medicine among infertile females with polycystic ovary syndrome (PCOS). Method: A total of 86 women with …
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Pakistani health authorities on Monday announced the completion of a successful clinical trial of Chinese traditional herbal medicine for treating COVID-19, as the South Asian nation enters a fifth wave of the pandemic driven by the Omicron variant. The Chinese medicine, Jinhua Qinggan Granules (JHQG) manufactured by Juxiechang (Beijing) pharmaceutical …
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Hormone therapy has been used in postmenopausal women for decades in clinical practice. With further analysis and newer studies, the benefits and risks of hormone therapy have been repeatedly verified and discussed. Hormone therapy is recommended for the treatment of vasomotor symptoms (VMS), genitourinary syndrome of menopause (GSM) and the …
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Background: Gouty arthritis is a common metabolic disease caused by long-term purine metabolism and elevated serum uric acid. In recent years, the incidence of gouty arthritis has been increasing year by year. As an effective method for treating gouty arthritis, acupuncture combined with herbal medicine has been widely used in clinical …
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Huang Qin Tang is a Traditional Chinese Medicine formula for ulcerative colitis. However, the pharmacology and molecular mechanism of Huang Qin Tang on ulcerative colitis is still unclear. Combined microarray analysis, network pharmacology, and molecular docking for revealing the therapeutic targets and molecular mechanism of Huang Qin Tang against ulcerative …
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Xiao Yao Wan has been widely applied in China to treat stress-related illnesses, such as migraine, depression, Parkinson’s disease, insomnia, hypertension. In this study aims to explore the effect of Xiao Yao Wan on chronic unpredictable mild stress-induced depression and its underlying mechanisms. Chronic unpredictable mild stress-induced depression rat models were established, …
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