Sjögren’s syndrome is an autoimmune disease, and its conventional treatment has exhibited limited therapeutic efficacy. Qing Zao Fang, a traditional Chinese medicine formula, is used in the treatment of Sjögren’s syndrome, but its chemical composition is complex, and its pharmacological mechanism is not clear. Therefore, this study aims to explore …

Background: Da Huang Zhe Chong San improves the inhibitory immune status of mice with hepatocellular carcinoma by regulating Treg/Th1 balance. Hypothesis/purpose: To study the multi-material basis and multi-mechanisms of Da Huang Zhe Chong San against hepatocellular carcinoma by regulating Treg/Th1 balance in vitro and in vivo. Methods: UPLC-MS/MS was used to detect the …

Objectives: The purpose of this study was to investigate the influence of Tai Chi on cardiorespiratory fitness in elderly people using meta-analysis. Methods: This study used seven electronic databases and data retrieved from randomized controlled trials (RCTs) investigating the role of Tai Chi on cardiorespiratory fitness in the elderly. All these 24 …

Purpose: Mild cognitive impairment is a general neurodegenerative disease. Moxibustion has been shown to have remarkable effect on cognitive improvement, however, less is known about the effect of moxibustion on mild cognitive impairment and its underlying neural mechanism. This study aimed to investigate the ameliorative brain network in mild cognitive impairment …

Objective: To systematically evaluate the clinical effect and safety of filiform-fire needle in the treatment of peripheral facial paralysis at different stages. Methods: Articles of the randomized controlled clinical trials (RCTs) about filiform fire needle treatment of peripheral facial paralysis published from the inception of the databases of CNKI, Wanfang, VIP, SinoMed, …

Objective: To observe and compare the effects of different acupuncture and moxibustionmethods at “San-yinjiao” (SP6) on uterine contraction and microcirculation in cold congealing dysmenorrhea rats, so as to explore its mechanism underlying treatment of dysmenorrhea. Methods: A total of 140 female SD rats were randomly divided into normal control, mo-del, perpendicular needling, …

Purpose: This study aims to evaluate the effectiveness and safety of oral Chinese herbal medicine in the treatment of knee osteoarthritis. Study design: Systematic review and meta-analysis of randomized controlled trials (RCTs). Materials and methods: A computer was used to retrieve all RCTs of Chinese herbal medicine in the treatment of knee osteoarthritis …

Background: Herpes zoster is a common skin disease that has a huge impact on the quality of life of sufferers. Antiviral therapy is a conventional treatment, but it still has limitations. This review evaluates the safety and efficacy of acupuncture in the treatment of herpes zoster. Methods: We identified randomized controlled trials …

Background: Since the beginning of the Coronavirus disease 2019 (COVID-19) pandemic, various complementary and alternative medicines have been used in clinical practice. In this overview, we summarized the evidence for complementary and alternative medicines interventions in the treatment of COVID-19 patients. Methods: For this overview, PubMed, Embase and Cochrane Library were searched …

Benefiting from the development of network pharmacology, Traditional Chinese Medicine (TCM) shows great potential in modern drug discovery. Recently, more and more TCM-related databases have been established for both academic and industry research, but they are still insufficient in data standardization, integrity, and precision. To better accelerate the TCM research …