Bupleurum chinense DC. (Chaihu) is a traditional Chinese medicine (TCM) used in the treatment of anxiety. But the anxiolytic mechanisms of bupleurum are still unclear. Therefore, this unknown is predicted by network pharmacology study with molecular docking in the present study. The components of bupleurum were obtained from the databases. …

Background: Coronavirus disease 2019 (COVID-19) keeps spreading globally. Chinese medicine (CM) exerts a critical role for the prevention or therapy of COVID-19 in an integrative and holistic way. However, mining and development of early, efficient, multisite binding CMs that inhibit the cytokine storm are imminent. Methods: The formulae were extracted retrospectively from …

Background: Needling and ibuprofen are often used clinically to treat primary dysmenorrhea. However, the difference between the efficacy and safety of the treatment of primary dysmenorrhe is not clear. This study evaluates the efficacy and safety of simple-needling for primary dysmenorrhepatients through a comparison with ibuprofen. Methods: A comprehensive search of 7 …

Background: Traditional Chinese medicine (TCM) is a type of alternative medicine that has been widely utilized in the prevention and treatment of mental diseases such as schizophrenia, ADHD, Alzheimer’s disease, and Tourette’s syndrome in many countries. However, the evidence regarding TCM’s effectiveness and safety in treating Tourette’s syndrome are conflicting. Therefore, …

Objectives: To study whether moxibustion can improve the learning and memory ability of APP/PS1 mice by reducing the pathological products Aβ and Tau protein via decreasing N6-methyladenosine (m6A). Methods: APP/PS1 mice were randomly divided into model group (APP/PS1) and moxibustion group (APP/PS1+Mox). C57BL/6J mice were used as a control group (Control). Learning and …

Background: To evaluate the efficacy of acupuncture in improving quality of life (QOL) and activities of daily living among elderly patients with hypertension and impaired physical mobility in home health care. Methods: Seventy participants were allocated randomly to receive either acupuncture together with antihypertensive drugs (n = 35) or antihypertensive drugs only …

Depression is a common psychiatric illness affecting over 300 million people globally. Acupuncture has been reported to be a safe complementary treatment for depression. This study is aimed to investigate the efficacy and mechanism of combining acupuncture with antidepressants in treating depression compared to the sole use of antidepressants. Seventy …

Aims: To investigate the additional benefit of acupuncture to pelvic floor exercise (PFE) on the improvement of urinary incontinence and quality of life (QoL) in women. Methods: This was a single-blinded randomized controlled trial in a tertiary university hospital. Women with urinary incontinence in various severity and types were randomized to receive …

Background: Complementary and alternative therapy is widely used to treat chronic obstructive pulmonary disease (COPD). A Chinese herbal medicine, Jian Pi Yi Fei Wan, have been shown to improve COPD patients’ quality of life, however long-term effectiveness has not been examined. Purpose: To investigate whether long-term treatment with Jian Pi Yi Fei …

Background: The clinical treatment of ulcerative colitis is limited. A traditional Chinese medicinal formula, Huang Qin Tang, is chronicled in Shang Han Lun and is widely used to ameliorate gastrointestinal disorders, such as ulcerative colitis; however, its mechanism is yet to be clarified. Purpose: The present study aimed to investigate the effect …