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Background: The clinical advantages of painless colonoscopy can reduce the fear and discomfort of patients and increase the detection rate of diseases. Propofol has the characteristics of fast effect and short action time. It is a common choice for painless endoscopic sedation and anesthetics. However, propofol can cause severe respiratory and circulatory depression. Therefore, it is important to find a way to reduce the dose of propofol.
Aim: To explore the effect of wrist-ankle acupuncture on propofol dose during colonoscopy.
Methods: Two hundred patients who were going to receive selective painless colonoscopy in Hebei Hospital of Traditional Chinese Medicine were selected and divided into wrist-ankle acupuncture group (n = 100) and control group (n = 100). After entering the operation room, patients were given 0.025 mg/kg nabufine intravenously and propofol at the initial dose of 0.5 mg/kg. In patients who did not fall asleep, propofol (10 mg/time) was given until loss of consciousness. Prior to anesthesia, patients in wrist-ankle acupuncture group were punctured by specialist in the inferior 1, 2 and 3 regions according to the zoning principle of wrist-ankle acupuncture.
The primary endpoint was required dose of propofol, and the secondary endpoints were the incidence of hypoxemia and hypotension. Furthermore, the following data were recorded: The operation time, wake-up time, incidence of nausea and vomiting, incidence of abdominal distention, post-colonoscopy pain, examiners’ satisfaction, patients’ satisfaction and Borg fatigue index.
Results: The induced dose of propofol and the total dose of propofol in wrist-ankle acupuncture group group were 80 mg and 110 mg, respectively, which were significantly lower than those in control group (P < 0.05). The incidences of hypoxemia and hypotension in the wrist-ankle acupuncture group group were 2.2% and 3.3%, respectively, significantly lower than those in the control group (P < 0.05). The incidence of abdominal distension in the wrist-ankle acupuncture group was 8.8%, which was significantly lower than that in the CON group (P < 0.05, 28.9%). The waking time of wrist-ankle acupuncture group was 3.26 ± 0.87 min, which was significantly lower than that of control group (6.06 ± 0.88 min, P < 0.05).
Conclusion: Wrist-ankle acupuncture can reduce the induction dose and total dose of propofol as well as the incidence of adverse reactions in painless colonoscopy without affecting the satisfaction of examiners and patients. This procedure is simple in operation and easy to promote in clinical practice.
Reference: https://pubmed.ncbi.nlm.nih.gov/35647164/