Chinese Herbal Research

Background: The clinical treatment of ulcerative colitis is limited. A traditional Chinese medicinal formula, Huang Qin Tang, is chronicled in Shang Han Lun and is widely used to ameliorate gastrointestinal disorders, such as ulcerative colitis; however, its mechanism is yet to be clarified. Purpose: The present study aimed to investigate the effect …

Sjögren’s syndrome is an autoimmune disease, and its conventional treatment has exhibited limited therapeutic efficacy. Qing Zao Fang, a traditional Chinese medicine formula, is used in the treatment of Sjögren’s syndrome, but its chemical composition is complex, and its pharmacological mechanism is not clear. Therefore, this study aims to explore …

Background: Da Huang Zhe Chong San improves the inhibitory immune status of mice with hepatocellular carcinoma by regulating Treg/Th1 balance. Hypothesis/purpose: To study the multi-material basis and multi-mechanisms of Da Huang Zhe Chong San against hepatocellular carcinoma by regulating Treg/Th1 balance in vitro and in vivo. Methods: UPLC-MS/MS was used to detect the …

Purpose: This study aims to evaluate the effectiveness and safety of oral Chinese herbal medicine in the treatment of knee osteoarthritis. Study design: Systematic review and meta-analysis of randomized controlled trials (RCTs). Materials and methods: A computer was used to retrieve all RCTs of Chinese herbal medicine in the treatment of knee osteoarthritis …

Background: Since the beginning of the Coronavirus disease 2019 (COVID-19) pandemic, various complementary and alternative medicines have been used in clinical practice. In this overview, we summarized the evidence for complementary and alternative medicines interventions in the treatment of COVID-19 patients. Methods: For this overview, PubMed, Embase and Cochrane Library were searched …

Benefiting from the development of network pharmacology, Traditional Chinese Medicine (TCM) shows great potential in modern drug discovery. Recently, more and more TCM-related databases have been established for both academic and industry research, but they are still insufficient in data standardization, integrity, and precision. To better accelerate the TCM research …

Ethnopharmacological relevance: Obesity in patients with schizophrenia is related to antipsychotic drug use, hypertension, diabetes, and dyslipidemia, which are critical risk factors for cardiovascular disease. Cassia seed is a traditional Chinese medicine that can be used to treat various eye disorders. Anthraquinone-containing Cassia seed were used to lower serum levels of …

Coronavirus disease 2019 (COVID-19) is an acute respiratory infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and it has become a public health concern worldwide. In addition to respiratory symptoms, some COVID‑19 patients also show various gastrointestinal symptoms and even consider gastrointestinal symptoms to be the first …

Traditional Chinese Medicine (TCM) plays a role in preventing and treating COVID-19 in China. Based on the manifestations and symptoms of COVID-19, our study used the data mining method to summarize related therapeutic experience left by predecessors who used TCM to treat epidemics in their eras. Initially, we collected abundant …

Background: Chemotherapy-induced peripheral neuropathy is a common adverse reaction of chemotherapy. Many studies have confirmed that traditional Chinese medicine (TCM) has unique advantages for treating CIPN. However, there is no standard TCM prescription in clinical practice or objective outcome index, and similar efficacy varies. In this study, a systematic review of …